Selected Publications (* Corresponding author) 1. Mingyang Li, Xinyang Jin, Tao Liu, Feng Fan, Feng Gao, Shuang Chai, Lihua Yang*. Nature Communications. 2022, 13, article no. 4137 [link] 2. Feng Gao, Tianyi Shao, Yunpeng Yu, Yujie Xiong*, Lihua Yang*. Surface-bound reactive oxygen species generating nanozymes for selective antibacterial action. Nature Communications 2021, 12, article no. 745 [link] 3. Lihua Yang, Vernita D. Gordon, Dallas R. Trinkle, Nathan W. Schmidt, Mathew A. Davis, Clarabelle DeVries, Abhigyan Som, John E. Cronan, Jr., Gregory N. Tew, Gerard C. L. Wong*. Mechanism of a prototypical synthetic membrane-active antimicrobial: Efficient hole-punching via negative curvature lipid targeting. Proceedings of the National Academy of Sciences of the United States of America 2008, 105, 20595-20600 [link]
4. Lihua Yang, Vernita D. Gordon, Abhijit Mishra, Abhigyan Som, Kirstin R. Purdy, Matthew A. Davis, Gregory N. Tew*, Gerard C.L. Wong*. Synthetic antimicrobial oligomers induce composition-dependent topological transition in membranes. Journal of the American Chemical Society 2007, 129, 12141-12147 [link]
5. Lihua Yang, Hongjun Liang, Thomas E. Angelini, John Butler, Robert Coridan, Jay X. Tang, Gerard C.L. Wong*. Self-assembled virus-membrane complexes. Nature Materials 2004, 3(9), 615-619 [link] Peer-reviewed Journal Papers (* Corresponding author) 35. Shuang Chai, Yutao Xie, Lihua Yang*. Antibacterial applications of elemental nanomaterials. Current Opinion in Solid State and Materials Science 2022, 26 (6), article no. 101043 (invited review) [link] 34. Mingyang Li, Xinyang Jin, Tao Liu, Feng Fan, Feng Gao, Shuang Chai, Lihua Yang*. Nature Communications 2022, 13, article no. 4137 [link] 33. Xinyang Jin, Feng Gao, Mingxin Qin, Yunpeng Yu, Yue Zhao, Tianyi Shao, Cai Chen, Wenhua Zhang*, Bin Xie*, Yujie Xiong*, Lihua Yang*, Yuen Wu*. How to Make Personal Protective Equipment Spontaneously and Continuously Antimicrobial (Incorporating Oxidase-like Catalysts). ACS Nano 2022, 16, 5, 7755-7771 [link] 32. Feng Fan, Bin Xie,* and Lihua Yang*. Promoting Nanoparticle Delivery Efficiency to Tumors by Locally Increasing Blood Flow There. ACS Applied Bio Materials 2021, 4, 7615-7625 [link] 31. Yajuan Liu, Zhiyuan Li, Feng Fan, Xianjun Zhu, Lingbo Jia, Muqing Chen, Pingwu Du, Lihua Yang*, and Shangfeng Yang*. Boosting Antitumor Sonodynamic Therapy Efficacy of Black Phosphorus via Covalent Functionalization. Advanced Science 2021, 8, article no. 2102422 [link]
30. Feng Fan, Lijun Jin, Lihua Yang*. pH-Sensitive Nanoparticles Composed Solely of Membrane-Disruptive Macromolecules for Treating Pancreatic Cancer. ACS Applied Materials & Interfaces 2021, 13, 12824–12835 [link]
29. Feng Gao, Tianyi Shao, Yunpeng Yu, Yujie Xiong*, Lihua Yang*. Surface-bound reactive oxygen species generating nanozymes for selective antibacterial action. Nature Communications 2021, 12, article no. 745 [link] 28. Binqian Yang, Feng Gao, Zhiyuan Li, Mingyang Li, Liang Chen, Yong Guan, Gang Liu, Lihua Yang*. Selective Entropy Gain-Driven Adsorption of Nanospheres onto Spherical Bacteria Endows Photodynamic Treatment with Narrow-Spectrum Activity. The Journal of Physical Chemistry Letters 2020, 11, 2788-2796
27. Zhiyuan Li, Taiming Zhang, Feng Fan, Feng Gao, Hengxing Ji*, Lihua Yang*. Piezoelectric Materials as Sonodynamic Sensitizers to Safely Ablate Tumors: A Case Study Using Black Phosphorus. The Journal of Physical Chemistry Letters 2020, 11, 1228-1238
26. Feng Fan, Ji-Gang Piao, Yangyang Zhao, Lijun Jin, Mingyang Li, Yucai Wang*, Lihua Yang*. Bioinspired Membrane-Disruptive Macromolecules as Drug-Free Therapeutics. ACS Applied Bio Materials 2020, 3, 1267-1275 25. Feng Gao, Lulu Xu, Binqian Yang, Feng Fan, and Lihua Yang*. Kill the Real with the Fake: Eliminate Intracellular Staphylococcus aureus Using Nanoparticle Coated with Its Extracellular Vesicle Membrane as Active-Targeting Drug Carrier. ACS Infectious Diseases 2019, 5, 218–227 24. Lulu Xu, Feng Gao, Feng Fan, Lihua Yang*. Platelet Membrane Coating Coupled with Solar Irradiation Endows A Photodynamic Nanosystem with Both Improved Antitumor Efficacy and Undetectable Skin Damage. Biomaterials 2018, 159, 59–67
23. Ji-Gang Piao, Feng Gao, Yunong Li, Lei Yu, Dong Liu, Zi-Bin Tan, Yujie Xiong*, Lihua Yang*, and Ye-Zi You*. pH-sensitive zwitterionic coating endows gold nanocage with improved tumor targeting and photothermal treatment efficacy. Nano Research 2018, 11, 3193–3204 22. Rui Zhu, Feng Gao, Ji-Gang Piao*,Lihua Yang*. Skin-Safe Photothermal Therapy Enabled by Responsive Release of Acid-Activated Membrane-Disruptive Polymer from Polydopamine Nanoparticle upon Very Low Laser Irradiation. Biomaterials Science 2017, 5, 1596-1602 (Invited Article in the “Biomaterials Science Emerging Investigators 2017” Themed Issue) 21. Liwei Hui, Shuai Qin, and Lihua Yang*. Upper Critical Solution Temperature Polymer, Photothermal Agent, and Erythrocyte Membrane Coating: An Unexplored Recipe for Making Drug Carriers with Spatiotemporally Controlled Cargo Release. ACS Biomaterials Science & Engineering 2016, 2, 2127–2132
20. Ji-Gang Piao, Dong Liu, Kan Hu, Limin Wang, Feng Gao, Yujie Xiong,* and Lihua Yang*. Cooperative Nanoparticle System for Photothermal Tumor Treatment without Skin Damage. ACS Applied Materials & Interfaces 2016, 8, 2847–2856
19. Yuntao Xie, Lihua Yang*. Calcium and Magnesium Ions Are Membrane-Active against Stationary-Phase Staphylococcus aureus with High Specificity. Scientific Reports 2016, 6, article number 20628
18. Ji-Gang Piao, Feng Gao, Lihua Yang*. Acid-Responsive Therapeutic Polymer for Prolonging Nanoparticle Circulation Lifetime and Destroying Drug-Resistant Tumors. ACS Applied Materials & Interfaces 2016, 8, 936–944
17. Liwei Hui, Jian-Liu Huang, Guanxiong Chen, Yanwu Zhu, Lihua Yang*. Antibacterial Property of Graphene Quantum Dots (Both Source Material and Bacterial Shape Matter). ACS Applied Materials & Interfaces 2016, 8, 20–25 16. Lulu Xu, Chen He, Liwei Hui, Yuntao Xie, Jia-Min Li, Wei-Dong He*, and Lihua Yang*. Bactericidal Dendritic Polycation Cloaked with Stealth Material via Lipase-Sensitive Intersegment Acquires Neutral Surface Charge without Losing Membrane-Disruptive Activity. ACS Applied Materials & Interfaces 2015, 7, 27602–27607 15. Guanxiong Chen, Zhiwen Zhuo, Kun Ni, Na Yeon Kim, Yuan Zhao, Zongwei Chen, Bin Xiang, Lihua Yang, Qun Zhang, Zonghoon Lee, Xiaojun Wu, Rodney S. Ruoff, Yanwu Zhu*. Rupturing C60 Molecules into Graphene-Oxide-like Quantum Dots: Structure, Photoluminescence, and Catalytic Application. Small 2015, 11, 5296–5304
14. Kan Hu, Yunjiang Jiang, Yuntao Xie, Hui Liu, Rui Liu, Zhi Zhao, Ren Lai*, Lihua Yang*. Small-Anion Selective Transmembrane “Holes” Induced by an Antimicrobial Peptide Too Short to Span Membranes. The Journal of Physical Chemistry B 2015, 119, 8553-8560
13. Liwei Hui, Jeffrey Auletta, Zhiyu Huang, Xiang Chen, Fei Xia, Shangfeng Yang, Haitao Liu, Lihua Yang*. Surface Disinfection Enabled by a Layer-by-Layer Thin Film of Polyelectrolyte-Stabilized Reduced Graphene Oxide upon Solar Near-Infrared Irradiation. ACS Applied Materials & Interfaces 2015, 7, 10511-10517 12. Ji-Gang Piao, Limin Wang, Feng Gao, Ye-Zi You*, Yujie Xiong*, Lihua Yang*. Erythrocyte Membrane Is an Alternative Coating to Polyethylene Glycol for Prolonging the Circulation Lifetime of Gold Nanocages for Photothermal Therapy. ACS Nano 2014, 8, 10414-10425
11. Xin Yang, Kan Hu, Guantai Hu, Danyao Shi, Yunjiang Jiang, Liwei Hui, Rui Zhu, Yuntao Xie, and Lihua Yang*. Long Hydrophilic-and-Cationic Polymers: A Different Pathway toward Preferential Activity against Bacterial over Mammalian Membranes. Biomacromolecules 2014, 15, 3267-3277
10. Liwei Hui, Ji-Gang Piao, Jeffrey Auletta, Kan Hu, Yanwu Zhu, Tara Meyer, Haitao Liu*, Lihua Yang*. Availability of the Basal Planes of Graphene Oxide Determines Whether It Is Antibacterial. ACS Applied Materials & Interfaces 2014, 6, 13183-13190 9. Yunjiang Jiang, Xin Yang, Rui Zhu, Kan Hu, Wang-Wei Lan, Fang Wu, Lihua Yang*. Acid-Activated Antimicrobial Random Copolymers: A Mechanism-Guided Design of Antimicrobial Peptide Mimics. Macromolecules 2013, 46, 3959-3964
8. Kan Hu, Nathan W. Schmidt, Rui Zhu, Yunjiang Jiang, Ghee Hwee Lai, Gang Wei, Edmund F. Palermo, Kenichi Kuroda*, Gerard C. L. Wong*, Lihua Yang*. A Critical Evaluation of Random Copolymer Mimesis of Homogeneous Antimicrobial Peptides. Macromolecules 2013, 46, 1908-1915 7. Gang Wei, Xin Liu, Li Yuan, Xiao-Jie Ju, Liang-Yin Chu, Lihua Yang*. Lipid Composition Influences Membrane-disrupting Activity of Antimicrobial Methacrylate Copolymers. Journal of Biomaterials Science, Polymer Edition 2011, 22, 2041-2061
~~~~~~~~~~~~~~~~~~~~~~~~~Prior to independent work~~~~~~~~~~~~~~~~~~~~~~~~~~
6. Abhigyan Som, Lihua Yang, Gerard C. L. Wong*, Gregory N. Tew*. Divalent Metal Ion Triggered Activity of A Synthetic Antimicrobial in Cardiolipin Membranes. Journal of the American Chemical Society 2009, 131, 15102-15103
5. Abhijit Mishra, Vernita D. Gordon, Lihua Yang, Robert Coridan, Gerard C. L. Wong*. HIV TAT domain induces 6nm pores in membranes. Angewandte Chemie International Edition 2008, 47, 2986-2989
4. Lihua Yang, Vernita D. Gordon, Dallas R. Trinkle, Nathan W. Schmidt, Mathew A. Davis, Clarabelle DeVries, Abhigyan Som, John E. Cronan, Jr., Gregory N. Tew, Gerard C. L. Wong*. Mechanism of a prototypical synthetic membrane-active antimicrobial: Efficient hole-punching via negative curvature lipid targeting. Proceedings of the National Academy of Sciences of the United States of America 2008, 105, 20595-20600
3. Lihua Yang, Vernita D. Gordon, Abhijit Mishra, Abhigyan Som, Kirstin R. Purdy, Matthew A. Davis, Gregory N. Tew*, Gerard C.L. Wong*. Synthetic antimicrobial oligomers induce composition-dependent topological transition in membranes. Journal of the American Chemical Society 2007, 129, 12141-12147
2. Lihua Yang, Hongjun Liang, Thomas E. Angelini, John Butler, Robert Coridan, Jay X. Tang, Gerard C.L. Wong*. Self-assembled virus-membrane complexes. Nature Materials 2004, 3(9), 615-619
1. Xiaogang Yang, Cun Li, Lihua Yang, Yan Yan, Yitai Qian*. Reduction-nitridation synthesis of titanium nitride nanocrystals. Journal of the American Ceramic Society 2003, 86(1), 206-208 |